Protein found in a biological system with a unique three-dimensional structure and biological activity is called a native protein. When a protein in its native form, is subjected to a physical change like change in temperature or a chemical change like change in pH, denaturation of protein takes place. Explain the cause.
Protein found in a biological system with a unique three-dimensional structure and biological activity is called a native protein. When a protein in its native form, is subjected to a physical change like change in temperature or a chemical change like change in pH, denaturation of protein takes place. Explain the cause.

Hydrogen bonds and other intermolecular interactions connect the amino acid residues in proteins.

The hydrogen bonds are disrupted when a physical or chemical change occurs, and the native protein unfolds.

Denaturation is a process in which secondary and tertiary structures are destroyed but the primary structure is preserved.