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Diffusion of gases occurs in the alveolar region only and not in the other parts of respiratory system. Why?

Solution: The alveoli present in the lungs are small air sacs that allow the fast exchange of gases. The alveolar membrane has a total thickness of less than a millimeter, and the outside surface of the membrane is in close proximity to the blood capillary connection.

A fine basement material distinguishes the endothelial membrane of blood capillaries and the alveolar membrane. The gases can easily diffuse through this thin barrier. The gas-diffusion is aided by higher levels of partial pressure of oxygen ($p{{O}_{2}}$) and lower levels of partial pressure of carbon dioxide ($pC{{O}_{2}}$) in alveolar air that comes close to the blood capillaries. All of these structural advantages seen in alveoli are not found in any other respiratory system structure. As a result, the gas diffusion phenomenon occurs exclusively in the alveolar region and not elsewhere.